Distinguishing PCOS from Endometriosis: What You Need to Know
March 28, 2025
Polycystic ovary syndrome (PCOS) and endometriosis are two common conditions that affect many individuals of reproductive age.

While both can impact fertility and overall well-being, they differ significantly in their causes, symptoms, and management approaches.
Understanding these differences is essential for making informed healthcare decisions and seeking appropriate guidance.
Endometriosis occurs when tissue similar to the womb lining grows outside it, leading to pain and other complications.
This misplaced tissue can develop in various areas, such as the ovaries, bowel, or pelvic lining, often causing severe discomfort, particularly during menstrual cycle.
One possible explanation for endometriosis is retrograde menstruation, where menstrual blood flows backward through the fallopian tubes, carrying tissue into the pelvic cavity.
Over time, this tissue implants and grows, triggering inflammation and pain. Scientists are still examining whether this or other theories can fully explain how endometriosis develops.
Endometriosis can impact multiple organs, with the ovaries being among the most commonly affected.
The presence of misplaced tissue often leads to chronic pain, irregular bleeding, and, in some cases, complications affecting fertility.
Polycystic ovary syndrome is a hormonal disorder that influences reproductive health and metabolism.
It is characterised by elevated levels of androgens (male hormones), irregular menstrual cycles, and, in some cases, small cysts on the ovaries.
PCOS results in hormonal disruptions that can interfere with ovulation, leading to symptoms such as acne, excessive hair growth, and weight gain.
Additionally, insulin resistance is commonly associated with PCOS, further impacting metabolic health and increasing the risk of conditions such as type 2 diabetes.
Contrary to its name, not all individuals with PCOS develop ovarian cysts.
The condition is primarily defined by irregular ovulation and hormonal imbalances, which can contribute to difficulties in conceiving and other long-term health concerns.
| Category | Endometriosis | Polycystic Ovary Syndrome (PCOS) |
| Causes | involves misplaced tissue growth (research suggests some hormone imbalance involved) | stems from hormonal imbalances |
| Symptoms | often associated with severe pelvic pain and abnormal bleeding | commonly leads to acne, weight gain, and irregular periods |
| Diagnosis | typically diagnosed through laparoscopy (examination of the pelvis and abdomen with a lighted tube with a camera at the end) | assessed using blood tests and ultrasound imaging. |
| Fertility Impact – both conditions can contribute to fertility challenges, though for different reasons | endometriosis may cause scarring | PCOS often disrupts ovulation. |
If you experience symptoms related to either condition, seeking guidance from a qualified healthcare professional is essential for proper evaluation and care.
Both conditions have complex origins, influenced by genetics, hormonal imbalances, and lifestyle factors.
Understanding diagnostic options can help individuals take proactive steps toward their health.
Common approaches include:
At AskAwayHealth, our goal is to provide reliable healthcare information and signposting to help you make informed decisions about your health.
We guide you through your healthcare journey by connecting you with the right services, offering education, and empowering you to manage your well-being effectively.
We also work to debunk common health myths by providing clear, evidence-based healthcare information.
Our mission is to ensure that you have access to the knowledge and resources you need to take charge of your health with confidence.
Understanding the differences between PCOS and endometriosis empowers individuals to take proactive steps toward better health.
Our role is to provide reliable information and educational resources, helping you make informed decisions about your healthcare journey.
For diagnosis, treatment, and management, consulting a medical professional can provide tailored advice and care.
More Reading

This post will be medically reviewed by March 2027
Editing and Disclaimer by AskAwayHealth Team
All AskAwayHealth articles are written by practising Medical Practitioners on various healthcare conditions to provide evidence-based guidance and help promote quality healthcare.
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Image Credits: Canva
https://www.kofinasfertility.com/patient-info/pcos-and-endometriosis – PCOS & Endometriosis: What’s the Difference & Can You Have Both?
https://www.verywellhealth.com/endometriosis-and-pcos-5295536 – What are the Differences Between PCOS and endometriosis?
https://www.hackensackmeridianhealth.org/en/healthu/2021/08/10/pcos-vs-endometriosis-whats-the-difference – PCOS vs. Endometriosis: What’s the Difference?
https://www.medicalnewstoday.com/articles/endometriosis-vs-pcos – Endometriosis vs PCOS: How to tell the difference
https://www.healthline.com/health/womens-health/endometriosis-vs-pcos – Endometriosis vs. PCOS: Symptoms, Diagnosis, Treatment
https://flo.health/menstrual-cycle/health/symptoms-and-diseases/pcos-vs-endometriosis – PCOS vs. endometriosis: What are the differences? – Flo
https://fertilityinstitute.com/pcos-vs-endometriosis-how-to-know-the-difference/ – PCOS vs. Endometriosis: How To Know The Difference | FINO
https://www.womenshealthmag.com/uk/health/female-health/a60465574/pcos-vs-endometriosis/ – PCOS and endometriosis can both mess with your period, but they’re totally different conditions
https://www.londonivfandgenetics.co.uk/the-difference-between-endometriosis-and-pcos/ – Understanding Endometriosis and PCOS | London IVF & Genetics
https://www.fertilityfamily.co.uk/blog/pcos-endometriosis-what-is-the-difference/ – PCOS & Endometriosis: What is the difference? – Fertility Family
https://pmc.ncbi.nlm.nih.gov/articles/PMC9361725/ – Polycystic Ovarian Syndrome and Endometriosis as Two Evil Extremes of Health Continuum
https://www.hcf.com.au/health-agenda/women/endometriosis/pcos-endometriosis-difference – Endometriosis vs PCOS: what’s the difference? | HCF
https://pmc.ncbi.nlm.nih.gov/articles/PMC8288001/ – Endometriosis and polycystic ovary syndrome are diametric disorders
https://femia.health/health-library/your-cycle/health/pcos-vs-endometriosis/ – PCOS vs Endometriosis: Causes, Symptoms & Differences – Femia
https://icarebetter.com/endometriosis-vs-pcos-whats-the-difference/ – Endometriosis vs. PCOS: What’s the Difference?
https://www.fertilityfamily.co.uk/blog/can-you-have-endometriosis-and-pcos/ – Can you Have Endometriosis and PCOS? – Fertility Family
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